SCHEMBL8053343

SCHEMBL8053343

O=C(O)c1ccc(OCCCCOc2ccccc2)cc1O

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.57
MAOB P27338 9/20 0.54
PKM P14618 1/20 0.53
ALDH1A1 P00352 1/20 0.53
KCNA3 P22001 1/20 0.52
PTPN11 Q06124 1/20 0.51
PLA2G4A P47712 1/20 0.51
MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8053501 0.98 PPARD (0.56) PPARDMAOBPKMALDH1A1PTPN11
SCHEMBL8064853 0.98 PPARD (0.56) PPARDMAOBPKMALDH1A1PTPN11
SCHEMBL8064850 0.98 PPARD (0.56) PPARDMAOBPKMALDH1A1PTPN11
SCHEMBL8062685 0.98 PPARD (0.56) PPARDMAOBPKMALDH1A1PTPN11
SCHEMBL8069528 0.97 PPARD (0.55) PPARDMAOBPKMALDH1A1PTPN11
SCHEMBL11454147 0.97 PPARD (0.61) PPARDMAOBPKMALDH1A1PLA2G4A
SCHEMBL5145630 0.95 PKM (0.59) PPARDMAOBPKMALDH1A1PLA2G4A
SCHEMBL7089122 0.94 PKM (0.57) PPARDMAOBPKMALDH1A1PLA2G4A
SCHEMBL7760683 0.91 PKM (0.54) PPARDMAOBPKMALDH1A1PLA2G4A
SCHEMBL8053504 0.88 HNF4A (0.63) PPARDMAOBPKMALDH1A1PLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4211989-A None JP disclosed
EP-0219302-B2 Recording materials FUJI PHOTO FILM CO LTD (JP) 2000-06-28 EP disclosed
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
JP-H04211989-A THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1992-08-03 JP disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4871713-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed
US-4861748-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-29 US disclosed
US-4839332-A AMINO-SUBSTITUTED FLUORENE AND ACID; DISCOLORATION INHIBITON, CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4803192-A COLORLESS DYE, AN AMINOPHENYLINDOLYLPHTHALIDE AND AN ELECTRON ACCEPTOR FUJI PHOTO FILM CO., LTD. (JP) 1989-02-07 US disclosed
US-4771034-A LEUCO DYE, SALICYCLIC ACID DERIVATIVE AS ELECTRON ACCEPTOR FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
EP-0219302-A2 Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1987-04-22 EP disclosed