SCHEMBL8053371

SCHEMBL8053371

O=C(O)C1CCCC=C1Cl

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.32
POLB P06746 2/20 0.31
HTT P42858 2/20 0.31
RAB9A P51151 1/20 0.31
MCL1 Q07820 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CASP1 P29466 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CXCR2 P25025 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8054932 0.83 CXCR2 (0.30) CXCR2
SCHEMBL164696 0.75 SIRT1 (0.32) MCL1ALDH1A1
SCHEMBL8041723 0.75 SIRT1 (0.35) POLBMCL1
Barium SCHEMBL30537014 0.73 SIRT1 (0.31) MCL1
Potassium SCHEMBL30537008 0.73 SIRT1 (0.31) MCL1
SCHEMBL28687284 0.73 SIRT1 (0.31) MCL1
SCHEMBL28689338 0.73 SIRT1 (0.31) MCL1
SCHEMBL29043688 0.73 SIRT1 (0.31) MCL1
Magnesium SCHEMBL30537017 0.73 SIRT1 (0.31) MCL1
SCHEMBL28036571 0.72 HCAR2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1285350-A 1-cyclenes tetraazolelinketone and the like BAYER AGROCHEM KK (JP) 2001-02-28 CN disclosed
CN-1061650-C 1-cycloalkenyl tetrazolinones BAYER AGROCHEM KK (JP) 2001-02-07 CN disclosed
EP-0728750-B1 1-Cycloalkenyltetrazolinones BAYER AGROCHEM KK (JP) 2000-05-17 EP disclosed
US-5654257-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1997-08-05 US disclosed
CN-1134418-A 1-cycloalkenyl tetrazolinones BAYER AGROCHEM KK (JP) 1996-10-30 CN disclosed
EP-0728750-A1 1-Cycloalkenyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-08-28 EP disclosed