Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423958 | 1.00 | NPSR1 (0.57) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL10717371 | 0.88 | HSD17B3 (0.62) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL7317275 | 0.86 | TDP1 (0.56) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL7317282 | 0.86 | TDP1 (0.56) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL12425722 | 0.82 | HDAC4 (0.69) | HDAC4HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL69146 | 0.81 | NPSR1 (0.74) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL271386 | 0.81 | NPSR1 (0.74) | NPSR1HDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL14619147 | 0.80 | CYP3A4 (0.53) | HDAC4HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL782211 | 0.80 | HDAC4 (0.47) | HDAC4HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL782212 | 0.80 | HDAC4 (0.47) | HDAC4HDAC3HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116687903-A | Application of cinnamic acid compound prepared from cinnamon active ingredient in preparation of product for inhibiting tyrosinase activity | 五邑大学 | 2023-09-05 | — | — | CN | disclosed |
| US-6143762-A | DRUGS AS DOPAMINE ANTAGONIST PSYCHOLOGICAL DISORDERS | SMITHKLINE BEECHAM, PLC (GB) | 2000-11-07 | — | — | US | disclosed |