Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747913 | 0.81 | TYR (0.39) | LMNATYRALDH1A1AKR1C3 | |
| SCHEMBL8955877 | 0.80 | TSHR (0.46) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL8545831 | 0.80 | TSHR (0.46) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL9621026 | 0.79 | TSHR (0.50) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL548066 | 0.79 | TSHR (0.50) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL1046560 | 0.78 | PDE2A (0.50) | TSHRALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL18243543 | 0.78 | TSHR (0.40) | GRIA4TSHRLMNATP53ALDH1A1 | |
| SCHEMBL8762246 | 0.77 | TSHR (0.48) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL292572 | 0.76 | TSHR (0.52) | GRIA4TSHRNR1H4LMNATYR | |
| SCHEMBL24209319 | 0.75 | PDE2A (0.63) | GRIA4TSHRNR1H4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102274527-B | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING INC | 2015-04-29 | — | — | CN | disclosed |
| US-6106999-A | SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS | MITSUI CHEMICALS (JP) | 2000-08-22 | — | — | US | disclosed |
| US-4742073-A | ANTIGLAUCOMA | BUNDGAARD HANS (DK) | 1988-05-03 | — | — | US | disclosed |