Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762246 | 0.82 | TSHR (0.48) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL1415320 | 0.81 | ESR1 (0.38) | LMNATYRMAPT | |
| SCHEMBL8053565 | 0.80 | GRIA4 (0.47) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL548066 | 0.79 | TSHR (0.50) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL9621026 | 0.79 | TSHR (0.50) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL12971364 | 0.78 | TSHR (0.44) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL678227 | 0.78 | PDE2A (0.50) | TSHRKIF11PDE2AALDH1A1AKR1C3 | |
| SCHEMBL11494429 | 0.78 | TSHR (0.39) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL22800995 | 0.78 | TSHR (0.47) | TSHRLMNATYRGRIA4NR1H4 | |
| SCHEMBL4963831 | 0.78 | TSHR (0.47) | TSHRLMNATYRGRIA4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299315-A | A kind of preparation method of acaricide fenazaquin | 杨子辉 | 2018-07-20 | — | — | CN | claimed |
| CN-108299315-A | A kind of preparation method of acaricide fenazaquin | 杨子辉 | 2018-07-20 | — | — | CN | disclosed |
| CN-106604941-A | Controlled radical polymerization | 巴斯夫欧洲公司 | 2017-04-26 | — | — | CN | disclosed |
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| EP-3114150-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| WO-2015134591-A1 | CONTROLLED RADICAL POLYMERIZATION | BASF SE (DE) | 2015-09-11 | — | — | WO | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| CN-101448800-A | Novel compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB (US) | 2009-06-03 | — | — | CN | disclosed |
| CN-1938266-A | Sulfonamide compounds for the treatment of neurodegenerative disorders | PFIZER PROD INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |
| CN-1649820-A | Compounds that modulate PPAR activity and methods for preparing the same | WARNER LAMBERT CO (US) | 2005-08-03 | — | — | CN | disclosed |
| EP-0837848-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001536-A1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI (FR) | 1997-01-16 | — | — | WO | disclosed |
| US-5026850-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4877787-A | Benzylthio pyridazinone derivatives, preparation thereof, and insecticidal acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0134439-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF AND INSECTICIDAL, ACARICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015762-A1 | CONTROLLED RADICAL POLYMERIZATION | GLO1, TET1, RIOX2 | TSHR 4673/4885LMNA 3944/4885TYR 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.