Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618202 | 0.82 | TSHR (0.48) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL10535737 | 0.82 | TSHR (0.48) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL2865480 | 0.81 | ADRB2 (0.41) | TSHRLMNATYRATMALDH1A1 | |
| SCHEMBL8053565 | 0.80 | GRIA4 (0.47) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL9621026 | 0.79 | TSHR (0.50) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL548066 | 0.79 | TSHR (0.50) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL677923 | 0.78 | PDE2A (0.50) | TSHRKIF11PDE2AALDH1A1AKR1C3 | |
| SCHEMBL11845496 | 0.78 | LMNA (0.43) | TSHRLMNATYRGRIA4ATM | |
| SCHEMBL8750404 | 0.78 | ESR1 (0.52) | TSHRALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL18475954 | 0.76 | NR1H4 (0.50) | TSHRLMNATYRGRIA4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322081-B | Synthesis method of alkyl alkenyl ketone | 南京工业大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-115322081-A | Synthesis method of alkyl alkenyl ketone | 南京工业大学 | 2022-11-11 | — | — | CN | disclosed |
| US-5486533-A | DIAZOLE OR TRIAZOLES WITH SILFIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0663904-A1 | FUNGICIDAL SUBSTITUTED AZOLE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008978-A1 | FUNGICIDAL SUBSTITUTED AZOLE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5026850-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4877787-A | Benzylthio pyridazinone derivatives, preparation thereof, and insecticidal acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0134439-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF AND INSECTICIDAL, ACARICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | disclosed |