Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975543 | 0.85 | TSHR (0.33) | TSHR | |
| SCHEMBL20658144 | 0.84 | THRB (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL8975929 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL20658161 | 0.79 | THRB (0.47) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11472202 | 0.78 | PTPN7 (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11475049 | 0.78 | PTPN7 (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3032195 | 0.78 | PTPN7 (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL29073225 | 0.77 | PTPN7 (0.44) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL3015199 | 0.76 | TSHR (0.35) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL30929762 | 0.75 | HTT (0.52) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686046-B1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-05-24 | — | — | EP | claimed |