Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975929 | 0.87 | TSHR (0.33) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL8053751 | 0.85 | HTT (0.42) | TSHR | |
| SCHEMBL2984055 | 0.77 | — | — | |
| SCHEMBL20658174 | 0.76 | TSHR (0.48) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL2919593 | 0.75 | ADRB2 (0.45) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL2990615 | 0.75 | ADRB2 (0.36) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL10972886 | 0.71 | PTPN7 (0.41) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL20658210 | 0.71 | ADRB2 (0.41) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL5167361 | 0.70 | TSHR (0.36) | TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL5167368 | 0.70 | TSHR (0.36) | TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |