Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041434 | 0.80 | POLB (0.40) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL8052926 | 0.78 | KDM4E (0.35) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL7494643 | 0.78 | DYRK1A (0.39) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| Hydrochloric Acid SCHEMBL7890565 | 0.76 | DYRK1A (0.38) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL7497270 | 0.75 | DYRK1A (0.33) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL7632455 | 0.75 | DYRK1A (0.39) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL8053507 | 0.74 | ALOX15 (0.40) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL8056632 | 0.73 | CHEK1 (0.36) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL7980854 | 0.72 | KDM4E (0.38) | DYRK1ACHEK1LIMK1CLK4KDM4E | |
| SCHEMBL7496405 | 0.71 | CA2 (0.33) | KDM4EALDH1A1HPGDHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |