SCHEMBL8054416

SCHEMBL8054416

O=c1[nH]nnn1C1=CCCC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041715 0.95 LMNA (0.39) LMNAMAPTCCNE1CDK2
SCHEMBL7981476 0.68 LMNA (0.31) LMNAMAPT
SCHEMBL8054877 0.68
SCHEMBL8041729 0.68
SCHEMBL8041737 0.68
SCHEMBL4672478 0.62 GAA (0.43) LMNAMAPT
SCHEMBL4307802 0.61 LMNA (0.46) LMNAMAPTCCNE1CDK2
SCHEMBL8603979 0.60 PFKFB3 (0.31)
SCHEMBL8687039 0.60 BCHE (0.41) LMNA
SCHEMBL29114362 0.60 LMNA (0.39) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728750-B1 1-Cycloalkenyltetrazolinones BAYER AGROCHEM KK (JP) 2000-05-17 EP disclosed
EP-0728750-A1 1-Cycloalkenyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-08-28 EP disclosed