Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054416 | 0.95 | LMNA (0.43) | LMNAMAPTCCNE1CDK2 | |
| SCHEMBL8041737 | 0.70 | — | — | |
| SCHEMBL8054877 | 0.70 | — | — | |
| SCHEMBL8041729 | 0.67 | — | — | |
| SCHEMBL10457256 | 0.65 | MAPT (0.43) | LMNAMAPTHDAC4HDAC2HDAC8 | |
| SCHEMBL8574458 | 0.63 | LMNA (0.35) | LMNAMAPTHDAC4HDAC2HDAC8 | |
| SCHEMBL22606188 | 0.62 | MGLL (0.36) | LMNAMAPTHDAC4HDAC2HDAC8 | |
| SCHEMBL12799401 | 0.61 | LMNA (0.91) | LMNAMAPT | |
| SCHEMBL8910664 | 0.61 | FEN1 (0.37) | LMNAMAPT | |
| SCHEMBL4672478 | 0.61 | GAA (0.43) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728750-B1 | 1-Cycloalkenyltetrazolinones | BAYER AGROCHEM KK (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5654257-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0728750-A1 | 1-Cycloalkenyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1996-08-28 | — | — | EP | disclosed |