Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.40 |
| ▸ | CTSK | P43235 | 15/20 | 0.40 |
| ▸ | CTSB | P07858 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957298 | 0.88 | ACE (0.50) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6950805 | 0.88 | ACE (0.50) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL22403247 | 0.85 | ACE (0.40) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL8050344 | 0.85 | SCN9A (0.34) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL13811785 | 0.80 | ACE (0.36) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL406298 | 0.79 | ATM (0.38) | CTSSACE | |
| SCHEMBL12330490 | 0.79 | AAK1 (0.51) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30674909 | 0.78 | KLK5 (0.46) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL15426849 | 0.77 | ACE (0.47) | ACE | |
| SCHEMBL16819882 | 0.77 | ACE (0.47) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| WO-2009083549-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2009-07-09 | — | — | WO | disclosed |