Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 7/20 | 0.33 |
| ▸ | CTSK | P43235 | 5/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054432 | 0.85 | CTSS (0.40) | AKT1CTSSCTSKCTSBCTSL | |
| SCHEMBL6957298 | 0.78 | ACE (0.50) | SCN9ACTSSCTSKCTSBCTSL | |
| SCHEMBL22403247 | 0.78 | ACE (0.40) | AKT1CTSSCTSKCTSBCTSL | |
| SCHEMBL6950805 | 0.78 | ACE (0.50) | SCN9ACTSSCTSKCTSBCTSL | |
| SCHEMBL13811785 | 0.72 | ACE (0.36) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL406298 | 0.71 | ATM (0.38) | CTSSACE | |
| SCHEMBL12330490 | 0.71 | AAK1 (0.51) | AKT1CTSSCTSKCTSBCTSL | |
| SCHEMBL28046578 | 0.71 | F10 (0.49) | — | |
| SCHEMBL28046576 | 0.71 | F10 (0.49) | — | |
| SCHEMBL4761847 | 0.70 | NFKB1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| WO-2009083549-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2009-07-09 | — | — | WO | disclosed |