Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286819 | 1.00 | HCAR2 (0.52) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL1286817 | 1.00 | HCAR2 (0.52) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL268634 | 0.90 | MGLL (0.55) | MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL624267 | 0.90 | MGLL (0.55) | MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL268635 | 0.90 | MGLL (0.55) | MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL19882477 | 0.86 | MGLL (0.45) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| Diethyl Maleate SCHEMBL2271770 | 0.86 | ALDH1A1 (0.73) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| Propane SCHEMBL4901497 | 0.86 | HCAR2 (0.53) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| Acrylic Acid Ethyl Ester SCHEMBL8159117 | 0.86 | ALDH1A1 (0.50) | HCAR2MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL7549900 | 0.86 | HCAR2 (0.55) | HCAR2MGLLALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2606863-B2 | — | — | 1997-05-07 | — | — | JP | claimed |
| EP-0267382-B1 | FUNCTIONALIZED POLYPHENYLENE ETHERS, METHOD OF PREPARATION, AND POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 1993-04-07 | — | — | EP | claimed |
| US-5015698-A | Polyphenylene ether-polyester copolymers, precursors therefor, compositions containing said copolymers, and methods for their preparation | GENERAL ELECTRIC COMPANY (US) | 1991-05-14 | — | — | US | claimed |
| US-4994531-A | Polyphenylene ethers or copolymers substituted with unsaturated glycidyl groups for compatibilizing engineering thermoplastics | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| US-4994525-A | GLYCIDYL ESTER FUNCTIONAL GROUPS | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| EP-0267382-A1 | Functionalized polyphenylene ethers, method of preparation, and polyphenylene ether-polyamide compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1988-05-18 | — | — | EP | claimed |
| WO-1987007281-A1 | FUNCTIONALIZED POLYPHENYLENE ETHERS, METHOD OF PREPARATION, AND POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 1987-12-03 | — | — | WO | claimed |
| US-10179835-B2 | Radical crosslinking of polyether carbonate polyols that have electron-poor and electron-rich double bonds | COVESTRO DEUTSCHLAND AG (DE) | 2019-01-15 | — | — | US | disclosed |
| US-20160200865-A1 | RADICAL CROSSLINKING OF POLYETHER CARBONATE POLYOLS THAT HAVE ELECTRON-POOR AND ELECTRON-RICH DOUBLE BONDS | COVESTRO DEUTSCHLAND AG (DE) | 2016-07-14 | — | — | US | disclosed |
| CN-105473637-A | Radical crosslinking of polyether carbonate polyols that have electron-poor and electron-rich double bonds | COVESTRO DEUTSCHLAND AG | 2016-04-06 | — | — | CN | disclosed |
| US-6077893-A | COMPOSITION CONTAINING FLOW PROMOTING AMIDE | GENERAL ELECTRIC CO. (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0732370-A2 | Poly(phenylene ether) compositions | GENERAL ELECTRIC COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0699716-A2 | Compositions of poly(phenylene ether) and polyester resins | GENERAL ELECTRIC COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| US-4994525-A | GLYCIDYL ESTER FUNCTIONAL GROUPS | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| US-4994531-A | Polyphenylene ethers or copolymers substituted with unsaturated glycidyl groups for compatibilizing engineering thermoplastics | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0268981-A2 | Thermoplastic resin composition | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| EP-0267382-A1 | Functionalized polyphenylene ethers, method of preparation, and polyphenylene ether-polyamide compositions prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1988-05-18 | — | — | EP | disclosed |
| EP-0248263-A2 | Polyphenylene ether-polyester copolymers precursors therefor, compositions containing said copolymers, and methods for their preparation | GENERAL ELECTRIC COMPANY (US) | 1987-12-09 | — | — | EP | disclosed |
| WO-1987007279-A1 | POLYPHENYLENE ETHER-POLYESTER COPOLYMERS, PRECURSORS THEREFOR, COMPOSITIONS CONTAINING SAID COPOLYMERS, AND METHODS FOR THEIR PREPARATION | GENERAL ELECTRIC COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |
| WO-1987007281-A1 | FUNCTIONALIZED POLYPHENYLENE ETHERS, METHOD OF PREPARATION, AND POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |