Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | XPO1 | O14980 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054468 | 1.00 | HPGD (0.47) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18227995 | 0.89 | MEN1 (0.60) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7273072 | 0.87 | GLO1 (0.61) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15026404 | 0.87 | GLO1 (0.61) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8956854 | 0.86 | BACE1 (0.48) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10085360 | 0.86 | ALDH1A1 (0.53) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8956851 | 0.86 | BACE1 (0.48) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21399813 | 0.83 | MEN1 (0.54) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16969110 | 0.83 | NPSR1 (0.55) | HPGDALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14113061 | 0.81 | KMT2A (0.53) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025349-A | ANTIARRHYTHMIC PROPERTIES, | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |