Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATF4 | P18848 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356382 | 0.92 | ATF4 (0.58) | SCN1ASCN5ASCN9ATSHRUSP2 | |
| SCHEMBL8042975 | 0.89 | TSHR (0.62) | SCN1ASCN5ASCN9ATSHRUSP2 | |
| SCHEMBL24225699 | 0.87 | SCN1A (0.55) | SCN1ASCN5ASCN9AUSP2MEN1 | |
| SCHEMBL22373890 | 0.86 | ATF4 (0.54) | SCN1ASCN5ASCN9AATF4 | |
| SCHEMBL24225652 | 0.81 | ATF4 (0.52) | ATF4 | |
| SCHEMBL24225633 | 0.81 | ATF4 (0.52) | ATF4 | |
| SCHEMBL20854551 | 0.79 | ATF4 (0.56) | TSHRUSP2MEN1KMT2AATF4 | |
| SCHEMBL21882081 | 0.79 | ATF4 (0.59) | ATF4 | |
| SCHEMBL29436900 | 0.79 | ATF4 (0.59) | ATF4 | |
| SCHEMBL4340211 | 0.78 | SCN5A (0.55) | SCN1ASCN5ASCN9ATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011032-A | Heterocyclic compounds for treating myocardial ischemia | PIERRE FABRE MEDICAMENT (FR) | 2000-01-04 | — | — | US | disclosed |