Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SCN1A | P35498 | 1/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24225699 | 0.90 | SCN1A (0.55) | SCN1ASCN5ASCN9AMEN1KMT2A | |
| SCHEMBL8054546 | 0.89 | SCN1A (0.52) | TSHRSCN1ASCN5ASCN9AMEN1 | |
| SCHEMBL29356382 | 0.87 | ATF4 (0.58) | TSHRSCN1ASCN5ASCN9AUSP2 | |
| SCHEMBL4340211 | 0.83 | SCN5A (0.55) | TSHRSCN1ASCN5ASCN9AMEN1 | |
| SCHEMBL22373890 | 0.81 | ATF4 (0.54) | SCN1ASCN5ASCN9A | |
| SCHEMBL7808692 | 0.81 | TSHR (0.75) | TSHRMEN1KMT2ACYP2D6ABCB1 | |
| Hydrochloric Acid SCHEMBL8055599 | 0.80 | TSHR (0.73) | TSHRMEN1KMT2ACYP2D6ABCB1 | |
| SCHEMBL621716 | 0.80 | CTSK (0.46) | SCN1ASCN5ASCN9A | |
| SCHEMBL5749820 | 0.80 | HTR2A (0.64) | TSHRMEN1KMT2AABCB1HTR2A | |
| SCHEMBL3351581 | 0.78 | SIGMAR1 (0.60) | CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011032-A | Heterocyclic compounds for treating myocardial ischemia | PIERRE FABRE MEDICAMENT (FR) | 2000-01-04 | — | — | US | disclosed |