SCHEMBL8054701

SCHEMBL8054701

CCCCCCCCCCCCCCCCCC(=O)C(O)(CO)C(O)C(=O)CCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.46
CES1 P23141 5/20 0.46
CES2 O00748 3/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384510 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8749109 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384626 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4431228 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10426860 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2823152 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8048379 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384533 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384429 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8051829 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP claimed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP claimed
WO-1996009810-A1 METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-04 WO claimed
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP disclosed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP disclosed
US-5750091-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1998-05-12 US disclosed
US-5700450-A Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-12-23 US disclosed
US-5352440-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 1994-10-04 US disclosed
EP-0373195-A1 COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. TUFTS COLLEGE (US) 1990-06-20 EP disclosed
EP-0373195-A4 COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. TUFTS COLLEGE (US) 1990-05-14 EP disclosed
WO-1989009258-A1 METHODS FOR INCREASING MELANIN CONTENT AND FOR INDUCING MELANOCYTE PROLIFERATION IN-VIVO AND IN-VITRO TRUSTEES OF TUFTS COLLEGE (US) 1989-10-05 WO disclosed