SCHEMBL8749109

SCHEMBL8749109

CCCCCCCCCCCCCCC(=O)C(O)C(O)(CO)C(=O)CCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.46
CES1 P23141 5/20 0.46
CES2 O00748 3/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8384510 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8054701 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384626 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4431228 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10426860 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2823152 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8048379 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384533 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8384429 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8051829 1.00 FAAH (0.46) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5358714-A Diacylglycerols as chemical activators of protein kinase C enzymes for inducing and increasing hair growth UNILEVER PATENT HOLDINGS B.V. (NL) 1994-10-25 US claimed
EP-0334585-B1 Cosmetic composition UNILEVER PLC (GB) 1994-09-14 EP claimed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP claimed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
US-5358714-A Diacylglycerols as chemical activators of protein kinase C enzymes for inducing and increasing hair growth UNILEVER PATENT HOLDINGS B.V. (NL) 1994-10-25 US disclosed
EP-0334585-B1 Cosmetic composition UNILEVER PLC (GB) 1994-09-14 EP disclosed
EP-0334586-B1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1994-05-18 EP disclosed
US-5081151-A Applying a hexosaccharic acid, salt or ester CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-01-14 US disclosed
US-5037643-A Increase hair growth UNILEVER PATENT HOLDINGS, B.V. (NL) 1991-08-06 US disclosed
EP-0403238-A2 Cosmetic composition UNILEVER PLC (GB) 1990-12-19 EP disclosed
US-4975441-A ENZYME INHIBITOR OF GLYCOSIDASE TO INCREASE HAIR GROWTH; TOPICAL UNILEVER PATENT HOLDINGS B.V. (NL) 1990-12-04 US disclosed
EP-0375388-A2 Cosmetic composition UNILEVER PLC (GB) 1990-06-27 EP disclosed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP disclosed
EP-0335554-A2 Cosmetic composition UNILEVER PLC (GB) 1989-10-04 EP disclosed
EP-0334586-A1 Carbohydrate lactam derivatives and their use in cosmetic compositions UNILEVER PLC (GB) 1989-09-27 EP disclosed
EP-0334585-A2 Cosmetic composition UNILEVER PLC (GB) 1989-09-27 EP disclosed