Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9721598 | 0.99 | HTR4 (0.76) | HTR4KCNH2 | |
| Water SCHEMBL9721589 | 0.99 | HTR4 (0.76) | HTR4KCNH2 | |
| Water SCHEMBL9721584 | 0.99 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL9728694 | 0.90 | HTR4 (0.80) | HTR4KCNH2 | |
| SCHEMBL9728308 | 0.90 | HTR4 (0.80) | HTR4KCNH2 | |
| SCHEMBL9022017 | 0.90 | HTR4 (0.75) | HTR4KCNH2 | |
| SCHEMBL9728381 | 0.90 | HTR4 (0.80) | HTR4KCNH2 | |
| SCHEMBL9728705 | 0.90 | HTR4 (0.80) | HTR4KCNH2 | |
| SCHEMBL1905248 | 0.90 | HTR4 (0.75) | HTR4KCNH2 | |
| SCHEMBL9021506 | 0.90 | HTR4 (0.75) | HTR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000029-A1 | (+)-NORCISAPRIDE USEFUL FOR 5-HT3 AND 5-HT4 MEDIATED DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999002496-A1 | (+)-NORCISAPRIDE USEFUL FOR 5-HT3 AND 5-HT4 MEDIATED DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-01-21 | — | — | WO | disclosed |