SCHEMBL8055023

SCHEMBL8055023

CCOC(=O)CCc1cccc(N(c2cccc(CCC(=O)OCC)c2)c2ccc(C)c(C)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.47
CYP4A11 Q02928 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.43
CYP4Z1 Q86W10 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX5 P09917 1/20 0.41
S1PR1 P21453 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
SYK P43405 2/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
P2RY12 Q9H244 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26534594 0.89 CYP4F2 (0.59) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL7756823 0.87 SMN1; SMN2 (0.49) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL5531196 0.86 CYP4F2 (0.55) CYP4F2CYP4A11CYP4Z1TDP1ALOX5
SCHEMBL26533932 0.85 CYP4F2 (0.54) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL10411875 0.82 CYP4F2 (0.53) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL11340512 0.81 THRB (0.52) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL4425984 0.80 CYP4F2 (0.64) CYP4F2CYP4A11CYP4Z1TDP1ALOX5
SCHEMBL18011700 0.79 CYP4F2 (0.64) CYP4F2CYP4A11SMN1; SMN2CYP4Z1TDP1
SCHEMBL14732613 0.79 CYP4F2 (0.44) CYP4F2CYP4A11SMN1; SMN2CYP4Z1S1PR1
SCHEMBL26534435 0.79 CYP4F2 (0.46) CYP4F2CYP4A11CYP4Z1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686879-B1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO LTD (JP) 2000-05-24 EP disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 US disclosed
EP-0687958-A1 Charge-transporting polymer and organic electron device using same FUJI XEROX CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 EP disclosed