SCHEMBL8055030

SCHEMBL8055030

O=C(O)C(C(=O)O)C(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
TP53 P04637 1/20 0.44
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
OR51E2 Q9H255 1/20 0.37
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ABCB11 O95342 1/20 0.35
F2 P00734 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C19 P33261 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN5 P54829 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29255 0.77 ALDH1A1 (0.46) TSHRTP53ALDH1A1LMNATHRB
SCHEMBL26660986 0.77 ALDH1A1 (0.46) TSHRTP53ALDH1A1LMNATHRB
Ammonia Solution, Strong SCHEMBL2587162 0.73 ALDH1A1 (0.43) TSHRTP53ALDH1A1LMNATHRB
SCHEMBL9248508 0.72 TSHR (0.64) TSHRTP53ALDH1A1LMNATHRB
Ethane SCHEMBL11652549 0.70 TP53 (0.47) TSHRTP53ALDH1A1LMNATHRB
Cadaverine Tartrate SCHEMBL6150968 0.70 TSHR (0.91) TSHRTP53ALDH1A1LMNATHRB
SCHEMBL1124153 0.69 TP53 (0.56) TSHRTP53OR51E2
SCHEMBL168369 0.67
Mucic Acid SCHEMBL77363 0.67 TSHR (0.69) TSHRTP53ALDH1A1LMNATHRB
Mucic Acid SCHEMBL17594183 0.67 TSHR (0.69) TSHRTP53ALDH1A1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
JP-10306090-A None JP disclosed
EP-3555161-B1 AN AQUEOUS DISPERSION OF POLYURETHANE COVESTRO DEUTSCHLAND AG (DE) 2025-08-20 EP disclosed
US-11685805-B2 Aqueous dispersion of polyurethane COVESTRO DEUTSCHLAND AG (DE) 2023-06-27 US disclosed
US-20210130532-A1 AN AQUEOUS DISPERSION OF POLYURETHANE COVESTRO DEUTSCHLAND AG (DE) 2021-05-06 US disclosed
CN-108069889-A A kind of synthetic method of azetidine -3- formic acid 上海西浦医药科技有限公司 2018-05-25 CN disclosed
JP-H10306090-A PRODUCTION OF 1,3-DIOXANE COMPOUND HUELS AG 1998-11-17 JP disclosed
CN-1090309-A Aqueous polyurethane resin dispersion liquid and preparation method thereof and its application in aqueous coating composition HERBERTS GMBH (DE) 1994-08-03 CN disclosed
EP-0268460-B1 NEW PERCUTANEOUS ABSORPTION ENHANCERS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE Macrochem Corporation (US) 1991-11-06 EP disclosed
US-4861764-A Percutaneous absorption enhancers, compositions containing same and method of use MACRO CHEM. CORP. (US) 1989-08-29 US disclosed
EP-0268460-A1 New percutaneous absorption enhancers, compositions containing same and method of use Macrochem Corporation (US) 1988-05-25 EP disclosed