SCHEMBL8055049

SCHEMBL8055049

Cc1ccccc1PCc1cc2ccccc2c(-c2cccc3ccccc23)c1CP(C(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
CYP2A6 P11509 1/20 0.31
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043541 0.86 ALDH1A1 (0.31) ALDH1A1CYP1A2HPGDHSD17B10GPR84
SCHEMBL8061394 0.83
SCHEMBL8056048 0.82
SCHEMBL8055047 0.78 CYP2A6 (0.33) ALDH1A1CYP1A2HPGDHSD17B10CYP2A6
SCHEMBL8059239 0.69
SCHEMBL8061359 0.69
SCHEMBL8043540 0.66 CYP2A6 (0.32) ALDH1A1CYP1A2HPGDHSD17B10CYP2A6
SCHEMBL4537883 0.66 GPR84 (0.37) ALDH1A1HPGDHSD17B10GPR84DHFR
SCHEMBL30332991 0.66 CES1 (0.41) ALDH1A1HPGDHSD17B10GPR84DHFR
SCHEMBL28933276 0.66 CES1 (0.41) ALDH1A1HPGDHSD17B10GPR84DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704449-B1 Process for the preparation of diphosphanes CELANESE CHEM EUROPE GMBH (DE) 2000-05-24 EP disclosed
US-5696296-A Diphosphines and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-09 US disclosed
EP-0704449-A1 Diphosphanes and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed