Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055417 | 1.00 | PTGIR (0.57) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL9007086 | 0.91 | PTGIR (0.53) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL8055530 | 0.87 | PTGIR (0.47) | PTGIRPTGER4PTGER3KDM4EALDH1A1 | |
| SCHEMBL8055531 | 0.87 | PTGIR (0.47) | PTGIRPTGER4PTGER3KDM4EALDH1A1 | |
| SCHEMBL9006886 | 0.87 | PTGIR (0.48) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8065993 | 0.85 | FABP4 (0.50) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL8065990 | 0.85 | FABP4 (0.50) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL7489580 | 0.81 | PTGIR (0.82) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL7499177 | 0.80 | PTGIR (0.81) | PTGIRPTGER4PTGER3FABP4KDM4E | |
| SCHEMBL7499185 | 0.80 | PTGIR (0.81) | PTGIRPTGER4PTGER3FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |