Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | METAP1 | P53582 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13406175 | 0.81 | KDM4E (0.50) | RAB9AALDH1A1KMT2AMAPTGAA | |
| SCHEMBL13019047 | 0.80 | KDM4E (0.53) | RAB9AALDH1A1MAPTGAANPSR1 | |
| SCHEMBL13406171 | 0.80 | KDM4E (0.53) | RAB9AALDH1A1KMT2AMAPTGAA | |
| SCHEMBL2061612 | 0.80 | KDM4E (0.70) | RAB9AALDH1A1KMT2AMAPTGAA | |
| SCHEMBL6259745 | 0.76 | KDM4E (0.49) | RAB9AALDH1A1KMT2AMAPTGAA | |
| SCHEMBL8371593 | 0.75 | ACHE (0.63) | ACHERAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL27610258 | 0.75 | TSHR (0.45) | RAB9AALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL13019048 | 0.74 | MEN1 (0.65) | RAB9AALDH1A1KMT2AMAPTNPSR1 | |
| SCHEMBL7965339 | 0.74 | KDM4E (0.81) | RAB9AALDH1A1KMT2AMAPTGAA | |
| Dipyridyl SCHEMBL9615229 | 0.74 | TSHR (0.78) | RAB9AALDH1A1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000229952-A | ZINC COMPLEX WITH QUINOXALINE COMPOUND AS LIGAND | KURARAY CO LTD | 2000-08-22 | — | — | JP | disclosed |
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |