Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055819 | 1.00 | CES2 (0.57) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL8055817 | 1.00 | CES2 (0.57) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL8055516 | 0.85 | CES2 (0.62) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL8055512 | 0.85 | CES2 (0.62) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL8055509 | 0.85 | CES2 (0.62) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL562773 | 0.81 | CES1 (0.52) | CES2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2505658 | 0.79 | CES2 (0.54) | CES2KMT2AMEN1LMNANPSR1 | |
| SCHEMBL2505653 | 0.79 | CES2 (0.54) | CES2KMT2AMEN1LMNANPSR1 | |
| SCHEMBL39834 | 0.78 | CES2 (0.71) | CES2SRD5A2KMT2AMEN1LMNA | |
| SCHEMBL30093723 | 0.78 | CES2 (0.71) | CES2SRD5A2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025349-A | ANTIARRHYTHMIC PROPERTIES, | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |