Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491486 | 0.82 | CES1 (0.45) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL524976 | 0.82 | CES1 (0.45) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL8055824 | 0.81 | CES2 (0.57) | CES2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8055817 | 0.81 | CES2 (0.57) | CES2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8055819 | 0.81 | CES2 (0.57) | CES2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4783569 | 0.79 | CES1 (0.56) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL2505658 | 0.79 | CES2 (0.54) | CES1CES2ALDH1A1TSHRRAB9A | |
| SCHEMBL2505653 | 0.79 | CES2 (0.54) | CES1CES2ALDH1A1TSHRRAB9A | |
| SCHEMBL28449348 | 0.79 | CES1 (0.48) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL8634365 | 0.78 | CES1 (0.54) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609318-B2 | Radiation-sensitive resin composition, method for forming resist pattern and polymer | JSR CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20120034560-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND POLYMER | JSR CORPORATION (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2193117-A1 | INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth a Corporation of the State of Delaware (US) | 2010-06-09 | — | — | EP | disclosed |
| US-20090023801-A1 | INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2009-01-22 | — | — | US | disclosed |
| WO-2009012205-A1 | INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023801-A1 | INHIBITORS OF BETA AMYLOID PRODUCTION | GYS1, APP, PSEN1 | CES1 127/4885CES2 1008/4885ALDH1A1 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.