Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742682 | 0.84 | TDP1 (0.47) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL2721414 | 0.83 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL5136229 | 0.82 | SMN1; SMN2 (0.50) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL14742742 | 0.82 | TDP1 (0.53) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL14742308 | 0.80 | TDP1 (0.55) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL125503 | 0.80 | TDP1 (0.52) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL2348040 | 0.79 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL14742530 | 0.78 | TDP1 (0.42) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL3187413 | 0.78 | TDP1 (0.50) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL523837 | 0.78 | CA2 (0.59) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069272-A | Simplified method for the production of vinyl glycine (2-aminobut-3-enoic acid) and a convenient resolution of a derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-30 | — | — | US | claimed |
| EP-0559927-B1 | A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative | HOECHST AG (DE) | 1997-03-05 | — | — | EP | claimed |
| EP-0559927-A1 | A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative | Hoechst Schering AgrEvo GmbH (DE) | 1993-09-15 | — | — | EP | claimed |
| US-9688789-B2 | Degradable polycations derived from amino acid vinyl esters | NATIONAL SCIENCE FOUNDATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-9688789-B2 | Degradable polycations derived from amino acid vinyl esters | NATIONAL SCIENCE FOUNDATION (US) | 2017-06-27 | — | — | US | disclosed |
| US-20140296462-A1 | DEGRADABLE POLYCATIONS DERIVED FROM AMINO ACID VINYL ESTERS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2014-10-02 | — | — | US | disclosed |
| US-20140296462-A1 | DEGRADABLE POLYCATIONS DERIVED FROM AMINO ACID VINYL ESTERS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2014-10-02 | — | — | US | disclosed |
| US-8796405-B2 | Degradable polycations derived from amino acid vinyl esters | NATIONAL SCIENCE FOUNDATION | 2014-08-05 | — | — | US | disclosed |
| US-8796405-B2 | Degradable polycations derived from amino acid vinyl esters | NATIONAL SCIENCE FOUNDATION | 2014-08-05 | — | — | US | disclosed |
| US-20130184423-A1 | DEGRADABLE POLYCATIONS DERIVED FROM AMINO ACID VINYL ESTERS | WISCONSIN ALUMINI RESEARCH FOUNDATION (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184423-A1 | DEGRADABLE POLYCATIONS DERIVED FROM AMINO ACID VINYL ESTERS | WISCONSIN ALUMINI RESEARCH FOUNDATION (US) | 2013-07-18 | — | — | US | disclosed |
| US-6069272-A | Simplified method for the production of vinyl glycine (2-aminobut-3-enoic acid) and a convenient resolution of a derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-30 | — | — | US | disclosed |
| EP-0559927-B1 | A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0559927-A1 | A simplified method for the production of vinyl glycine (2-aminobut-3-enioc acid) and a convenient resolution of a derivative | Hoechst Schering AgrEvo GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |