Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13471245 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL7154752 | 0.88 | MAOA (0.47) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL22175642 | 0.85 | MAOA (0.55) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL21738506 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL1631203 | 0.84 | MAOA (0.44) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL1276792 | 0.83 | TDP1 (0.49) | SMN1; SMN2TDP1MAOAMAOBMEN1 | |
| SCHEMBL8056145 | 0.82 | TDP1 (0.43) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL21416167 | 0.81 | CTSK (0.45) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL6823130 | 0.81 | CA12 (0.41) | SMN1; SMN2TSHRTDP1MAOAMAOB | |
| SCHEMBL434612 | 0.81 | CA12 (0.43) | SMN1; SMN2TSHRTDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151843-A1 | TARGETED UNIVERSAL DELIVERY SYSTEM OF DON AND OTHER DRUGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-07-18 | — | — | WO | disclosed |
| US-11389464-B2 | Arginase inhibitors as therapeutics | MARS, INCORPORATED (US) | 2022-07-19 | — | — | US | disclosed |
| US-10377699-B2 | Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue | THE UNIVERSITY OF HONG KONG (CN) | 2019-08-13 | — | — | US | disclosed |
| EP-1866347-B1 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS TECH USA LLC (US) | 2018-05-09 | — | — | EP | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| WO-2017007701-A1 | ANTIVIRAL PHOSPHODIAMIDE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2017-01-12 | — | — | WO | disclosed |
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | THE UNIVERSITY OF HONG KONG (CN) | 2015-05-07 | — | — | US | disclosed |
| US-8288606-B2 | Magnesium, titanium, and halogen; internal electron donor, ethyl N-Boc-sarcosine, ethyl N-propionyl sarcosine, ethyl N-Boc-pipercolinate, N-carbobenzyloxy-L-proline methyl ester; polymerize propylene and ethylene or alpha-olefin; internal modifier which does not contain a phthalate derivative | INEOS USA LLC (US) | 2012-10-16 | — | — | US | disclosed |
| US-20080125614-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2008-05-29 | — | — | US | disclosed |
| EP-1866347-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006110234-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-1991004268-A1 | [N-(η-GLUTAMYL)GLYCYL]ALANINE DERIVATIVES | SANDOZ LTD. (CH) | 1991-04-04 | — | — | WO | disclosed |
| US-4970297-A | CONTAINING ISOXAZOLE RING | SYNTEX (U.S.A.) INC. (US) | 1990-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125614-A1 | Propylene polymer catalyst donor component | RAD52, PGR, DRD2 | SMN1; SMN2 2741/4885TSHR 341/4885TDP1 1259/4885 |
| US-10377699-B2 | Daptomycin analogues and a method for the preparation of daptomycin or a daptomycin analogue | SCD, SCD5, FASN | SMN1; SMN2 4047/4885TSHR 2347/4885TDP1 4270/4885 |
| US-11389464-B2 | Arginase inhibitors as therapeutics | ARG1, ARG2, PRMT1 | SMN1; SMN2 3461/4885TSHR 573/4885TDP1 1099/4885 |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | ERG28, RPL23, RPL10 | SMN1; SMN2 4749/4885TSHR 4491/4885TDP1 4057/4885 |
| US-20150126707-A1 | DAPTOMYCIN ANALOGUES AND A METHOD FOR THE PREPARATION OF DAPTOMYCIN OR A DAPTOMYCIN ANALOGUE | SCD, SCD5, FASN | SMN1; SMN2 3944/4885TSHR 2372/4885TDP1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.