SCHEMBL8056239

SCHEMBL8056239

CCc1cc2c(cc1C(=O)N=C(N)N)S(=O)(=O)C(C)CC2

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060659 0.88
SCHEMBL8057367 0.85
SCHEMBL8058122 0.80
SCHEMBL8058167 0.80
SCHEMBL8056246 0.79 DRD2 (0.37)
SCHEMBL8063031 0.78 SLC9A1 (0.46) SLC9A1
SCHEMBL8056998 0.78
SCHEMBL8062734 0.78
SCHEMBL8057336 0.77
SCHEMBL8056192 0.77 HTR2B (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6028069-A Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) 2000-02-22 US disclosed