Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 7/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057034 | 0.81 | HTR2B (0.41) | HTR2BHTR7SLC9A1 | |
| SCHEMBL8058147 | 0.80 | — | — | |
| SCHEMBL8045055 | 0.79 | CA12 (0.45) | — | |
| SCHEMBL8060822 | 0.73 | HTR2B (0.46) | HTR2BHTR7SLC9A1 | |
| SCHEMBL8057020 | 0.73 | SLC9A1 (0.48) | HTR2BHTR7SLC9A1 | |
| SCHEMBL8056208 | 0.72 | HTR2B (0.44) | HTR2BHTR7SLC9A1SLC9A2 | |
| SCHEMBL8062892 | 0.72 | HTR2B (0.42) | HTR2BHTR7SLC9A1SLC9A2 | |
| SCHEMBL8056192 | 0.71 | HTR2B (0.44) | HTR2BHTR7 | |
| SCHEMBL8056274 | 0.70 | HTR2B (0.46) | HTR2BHTR7 | |
| SCHEMBL8060706 | 0.70 | HTR2B (0.42) | HTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |