Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 2/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056330 | 0.84 | PDE4A (0.43) | SLC2A1GAAHSD17B10SYK | |
| SCHEMBL27532524 | 0.81 | ADORA3 (0.35) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL27694799 | 0.81 | ADORA3 (0.35) | SLC2A1 | |
| SCHEMBL27763562 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL8592141 | 0.69 | CYP1A2 (0.44) | GAACYP2C19HSD17B10GABRR1 | |
| SCHEMBL8768252 | 0.69 | GABRR1 (0.40) | CYP2C19HSD17B10GABRR1SYK | |
| SCHEMBL27736777 | 0.65 | ADORA3 (0.31) | — | |
| SCHEMBL239665 | 0.64 | ADORA2A (0.36) | SLC2A1GAA | |
| SCHEMBL6322513 | 0.64 | ADORA2A (0.36) | SLC2A1 | |
| SCHEMBL28900808 | 0.64 | BRD4 (0.39) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042349-A1 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999020643-A9 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999020643-A1 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-04-29 | — | — | WO | disclosed |