Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.81 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.81 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220209 | 1.00 | PTGS1 (0.81) | PTGS1PTGS2MAPK9MMEKMT2A | |
| SCHEMBL1056332 | 0.90 | PTGS1 (1.00) | PTGS1PTGS2HPGDALDH1A1CYP1A2 | |
| SCHEMBL15695562 | 0.90 | PTGS1 (0.66) | PTGS1PTGS2MAPK9KMT2AHPGD | |
| SCHEMBL8796435 | 0.90 | PTGS1 (0.66) | PTGS1PTGS2MAPK9KMT2AHPGD | |
| SCHEMBL27598809 | 0.88 | PTGS1 (0.63) | PTGS1PTGS2MAPK9KMT2AHPGD | |
| SCHEMBL9577360 | 0.87 | PTGS1 (0.62) | PTGS1PTGS2MAPK9MMEKMT2A | |
| SCHEMBL18252774 | 0.86 | PTGS1 (0.61) | PTGS1PTGS2MAPK9KMT2AHPGD | |
| SCHEMBL8035766 | 0.85 | PTGS1 (0.59) | PTGS1PTGS2MAPK9MMEKMT2A | |
| SCHEMBL28574450 | 0.85 | PTGS1 (0.59) | PTGS1PTGS2MAPK9KMT2AHPGD | |
| SCHEMBL5717640 | 0.85 | PTGS2 (0.59) | PTGS1PTGS2KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | claimed |
| EP-4249470-B1 | METHOD FOR PREPARING ALPHA-AMINO ACIDS | PHILIPPS UNIV MARBURG (DE) | 2024-11-13 | — | — | EP | disclosed |
| CN-117586259-A | Spirocyclic MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-4249470-A1 | METHOD FOR PREPARING ALPHA-AMINO ACIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112979625-A | Synthesis method and application of piperlongumine | 广西馨海药业科技有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-109010827-A | Chlorambucil-poly-dopamine prodrug nanoparticle antitumor application thereof | 上海交通大学 | 2018-12-18 | — | — | CN | disclosed |
| CN-108383765-A | The synthesis of Chlorambucil-dopamine conjugate and the preparation of prodrug nano-particle | 上海交通大学 | 2018-08-10 | — | — | CN | disclosed |
| US-8785474-B2 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions | GRUENENTHAL GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8785655-B2 | Ionic liquid solvents | DUBLIN CITY UNIVERSITY (IE) | 2014-07-22 | — | — | US | disclosed |
| WO-1996031492-A1 | THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-10-10 | — | — | WO | disclosed |
| WO-1996006093-A1 | 7-AZABICYCLO[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS | UNIVERSITY OF VIRGINIA (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0691971-A1 | 7-AZABICYCLO- 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022868-A1 | 7-AZABICYCLO-[2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS ANALGESICS AND ANTI-INFLAMMATORY AGENTS | UNIVERSITY OF VIRGINIA (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5334598-A | Have endothelin antagonist activity; useful in treating cardiovascular disorders, hypertension, inflammatory diseases and asthma | MERCK & CO., INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5312828-A | Substituted imidazoles having angiotensin II receptor blocking activity | SMITHKLINE BEECHAM CORPORATION A CORP. OF PENNSYLVANIA | 1994-05-17 | — | — | US | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0386243-A1 | PLATINUM (II) COMPLEXES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-3962282-A | JUVENILE HORMONE MIMICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |