Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.51 |
| ▸ | EED | O75530 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006873 | 0.87 | PTGIR (0.52) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8065601 | 0.86 | PTGIR (0.62) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL27344473 | 0.85 | PTGIR (0.47) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8065136 | 0.83 | KDM4E (0.44) | PTGIRRXRARXRBKDM4ELMNA | |
| SCHEMBL8065255 | 0.80 | PTGIR (0.71) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8074838 | 0.79 | KDM4E (0.46) | PTGIRHTR1ARXRARXRBKDM4E | |
| SCHEMBL27579519 | 0.76 | PTGIR (0.50) | PTGIRHTR1ASLC6A4PTGER4PTGER3 | |
| SCHEMBL27332377 | 0.75 | PTGIR (0.45) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL7490972 | 0.75 | PTGIR (0.49) | PTGIRHTR1ASLC6A4RXRARXRB | |
| SCHEMBL7960388 | 0.74 | PTGIR (0.51) | PTGIREEDHTR1ASLC6A4PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |