Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056752 | 0.87 | PTGIR (0.51) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL8065601 | 0.86 | PTGIR (0.62) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL9006854 | 0.85 | PTGIR (0.44) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL9007180 | 0.84 | PTGIR (0.72) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL27344473 | 0.82 | PTGIR (0.47) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL9006816 | 0.81 | NR4A2 (0.45) | PTGIRNR4A2RXRARXRBRXRG | |
| SCHEMBL9006986 | 0.81 | PTGIR (0.53) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL9006831 | 0.79 | PTGIR (0.55) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL7490338 | 0.78 | PTGIR (0.72) | PTGIRPTGER4PTGER3TBXA2RPTGER2 | |
| SCHEMBL7487193 | 0.78 | PTGIR (0.72) | PTGIRPTGER4PTGER3TBXA2RPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |