Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060420 | 0.89 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8071083 | 0.88 | FAAH (0.56) | KMT2ASMN1; SMN2ALDH1A1MAPTFAAH | |
| SCHEMBL8072755 | 0.87 | FAAH (0.43) | SMN1; SMN2ALDH1A1MAPTFAAHCACNA1G | |
| SCHEMBL8072793 | 0.86 | CACNA1G (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8066478 | 0.82 | MAPT (0.51) | MEN1KMT2AMAPTFAAHLMNA | |
| SCHEMBL8072796 | 0.82 | MAPK1 (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8071116 | 0.79 | MAPT (0.48) | MEN1KMT2AALDH1A1MAPTFAAH | |
| SCHEMBL8068738 | 0.79 | FAAH (0.56) | KMT2ASMN1; SMN2ALDH1A1MAPTFAAH | |
| SCHEMBL8902949 | 0.77 | FAAH (0.54) | KMT2ASMN1; SMN2ALDH1A1MAPTFAAH | |
| SCHEMBL8071036 | 0.77 | FAAH (0.54) | KMT2ASMN1; SMN2ALDH1A1MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057311-A | TREATING EATING DISORDERS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-02 | — | — | US | disclosed |
| WO-1997032860-A1 | BENZODIAZONINE DERIVATIVES BINDING TO CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |