Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 7/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060827 | 0.82 | KDM4E (0.33) | CFTRNOTUMMAPTSOS1ALDH1A1 | |
| SCHEMBL8045255 | 0.81 | KDM4E (0.38) | MAPTALDH1A1HSD17B10KDM4EGLA | |
| SCHEMBL8057300 | 0.78 | CFTR (0.46) | CFTRNOTUMMAPTSOS1ALDH1A1 | |
| SCHEMBL8057109 | 0.78 | ALDH1A1 (0.34) | MAPTALDH1A1HSD17B10KDM4EGLA | |
| SCHEMBL8057039 | 0.76 | CFTR (0.41) | CFTRNOTUMMAPTSOS1MBOAT4 | |
| SCHEMBL8062894 | 0.72 | CFTR (0.40) | CFTRNOTUMMAPTSOS1P4HB | |
| SCHEMBL8056417 | 0.71 | CFTR (0.39) | CFTRNOTUMMAPTSOS1 | |
| SCHEMBL8056939 | 0.71 | CA1 (0.46) | NOTUMMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL8062790 | 0.70 | NOTUM (0.43) | CFTRNOTUMMAPTSOS1 | |
| SCHEMBL24983697 | 0.70 | CFTR (0.51) | CFTRNOTUMMAPTSOS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |