SCHEMBL8057508

SCHEMBL8057508

C=CC=CC.C[Ti](C)(NC(=O)c1ccccc1)C1C=Cc2ccccc21.[SiH4]

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060949 0.93 MEN1 (0.32) MEN1KMT2A
Butadiene SCHEMBL8466562 0.92 MEN1 (0.33) MEN1KMT2A
SCHEMBL8601079 0.89 MEN1 (0.36) MEN1KMT2A
SCHEMBL8056636 0.87 MEN1 (0.30) MEN1KMT2A
SCHEMBL8465654 0.85 MEN1 (0.33) MEN1KMT2A
SCHEMBL8678439 0.85 MEN1 (0.33) MEN1KMT2A
SCHEMBL8057554 0.84 GAA (0.39) MEN1KMT2A
SCHEMBL8060999 0.83 MEN1 (0.30) MEN1KMT2A
SCHEMBL8466565 0.82 MEN1 (0.31) MEN1KMT2A
SCHEMBL8063166 0.82 GAA (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0822937-B1 SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES DOW CHEMICAL CO (US) 2000-05-17 EP disclosed
US-5491246-A Synthesis of group 4 metal diene complexes THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed