Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057508 | 0.93 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8601079 | 0.93 | MEN1 (0.36) | MEN1KMT2ANPC1MAPTRAB9A | |
| Butadiene SCHEMBL8466562 | 0.89 | MEN1 (0.33) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8057554 | 0.88 | GAA (0.39) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8060999 | 0.87 | MEN1 (0.30) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8678439 | 0.87 | MEN1 (0.33) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8465654 | 0.87 | MEN1 (0.33) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8056636 | 0.86 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8063166 | 0.85 | GAA (0.41) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL8056648 | 0.85 | SIGMAR1 (0.32) | NPC1RAB9ASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822937-B1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | DOW CHEMICAL CO (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0822937-A1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034001-A1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1996-10-31 | — | — | WO | disclosed |
| US-5491246-A | Synthesis of group 4 metal diene complexes | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |