Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057554 | 0.95 | GAA (0.39) | GAAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8601079 | 0.88 | MEN1 (0.36) | GAAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8060949 | 0.85 | MEN1 (0.32) | MEN1KMT2AMAPK1MAPTNPC1 | |
| Butadiene SCHEMBL8466562 | 0.84 | MEN1 (0.33) | MEN1KMT2AALDH1A1MAPK1MAPT | |
| SCHEMBL8060999 | 0.83 | MEN1 (0.30) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8465654 | 0.82 | MEN1 (0.33) | GAAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8678439 | 0.82 | MEN1 (0.33) | MEN1KMT2AALDH1A1MAPK1MAPT | |
| SCHEMBL8057508 | 0.82 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL8056648 | 0.81 | SIGMAR1 (0.32) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8056636 | 0.80 | MEN1 (0.30) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822937-B1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | DOW CHEMICAL CO (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0822937-A1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034001-A1 | SYNTHESIS OF GROUP 4 METAL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1996-10-31 | — | — | WO | disclosed |