Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998105 | 0.91 | NPC1 (0.64) | MEN1KMT2ARAB9ANPC1TNF | |
| SCHEMBL8061909 | 0.86 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL21247046 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL21247359 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2ARAB9ANPC1TNF | |
| SCHEMBL3629758 | 0.76 | MEN1 (0.80) | MEN1KMT2ARAB9ANPC1TNF | |
| SCHEMBL22699615 | 0.76 | CNR2 (0.47) | MEN1KMT2ARAB9ANPC1TNF | |
| SCHEMBL21247226 | 0.75 | KDR (0.55) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12998090 | 0.73 | MEN1 (0.55) | MEN1KMT2ARAB9ANPC1TNF | |
| SCHEMBL1490568 | 0.71 | MEN1 (0.49) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL417864 | 0.71 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076454-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2009-06-18 | — | — | WO | disclosed |