Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medronic Acid SCHEMBL8057993 | 0.88 | KDM4E (0.50) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL29071034 | 0.83 | MEN1 (0.61) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL20580623 | 0.83 | MEN1 (0.61) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL29377463 | 0.83 | MEN1 (0.61) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL7727917 | 0.83 | MEN1 (0.61) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL11120537 | 0.83 | MEN1 (0.61) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL11664356 | 0.82 | MEN1 (0.48) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL2852663 | 0.81 | MEN1 (0.42) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL2029282 | 0.78 | MEN1 (0.55) | KDM4EMEN1KMT2AGAACYP2C9 | |
| Morpholine SCHEMBL412425 | 0.78 | MEN1 (0.55) | KDM4EMEN1KMT2AGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177525-A1 | METAL COMPLEX COMPOUND, CANCER THERAPEUTIC COMPOSITION COMPRISING THE METAL COMPLEX COMPOUND AS ACTIVE INGREDIENT, AND INTERMEDIATE FOR PRODUCTION OF THE METAL COMPLEX COMPOUND | TMRC Co., Ltd. (JP) | 2010-04-21 | — | — | EP | disclosed |