Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.47 |
| ▸ | HTR7 | P34969 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060894 | 0.84 | HTR2B (0.50) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8057055 | 0.78 | — | — | |
| SCHEMBL8056486 | 0.78 | HTR7 (0.42) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8056488 | 0.78 | HTR7 (0.42) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8060876 | 0.77 | HTR2B (0.48) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8058220 | 0.77 | — | — | |
| SCHEMBL8056982 | 0.77 | HTR7 (0.46) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8058149 | 0.75 | CA1 (0.44) | — | |
| SCHEMBL8062999 | 0.74 | HTR7 (0.49) | HTR2BHTR7DRD2ADRA1DHTR2A | |
| SCHEMBL8056907 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |