Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058311 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ATMHPGDTSHREPHX1 | |
| SCHEMBL8575692 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ATMHPGDEPHX1ACHE | |
| SCHEMBL8575690 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ATMHPGDEPHX1ACHE | |
| SCHEMBL8058305 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ATMHPGDTSHREPHX1 | |
| SCHEMBL8058307 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ATMHPGDTSHREPHX1 | |
| SCHEMBL11631150 | 0.75 | EPHX1 (0.47) | ALDH1A1EPHX1ACHE | |
| SCHEMBL11631146 | 0.75 | EPHX1 (0.47) | ALDH1A1EPHX1ACHE | |
| SCHEMBL15084802 | 0.74 | — | — | |
| SCHEMBL11451201 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ATMHPGDTSHREPHX1 | |
| SCHEMBL11626000 | 0.73 | EPHX1 (0.50) | TSHREPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-1003727-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007685-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |