Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18104887 | 0.81 | FFAR1 (0.50) | FFAR1PTGDR2LMNAGAAPOLB | |
| SCHEMBL3161990 | 0.80 | FFAR1 (0.52) | FFAR1PTGDR2LMNAGAAPOLB | |
| SCHEMBL15841080 | 0.78 | GRM5 (0.41) | PTGDR2GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL20089255 | 0.77 | FFAR1 (0.45) | FFAR1PTGDR2LMNAGAAPOLB | |
| SCHEMBL27014452 | 0.77 | FFAR4 (0.48) | FFAR1LMNAGAASMN1; SMN2POLB | |
| SCHEMBL15841077 | 0.76 | FFAR1 (0.45) | FFAR1GAANPC1RAB9AKDM4E | |
| SCHEMBL459924 | 0.75 | FFAR1 (0.48) | FFAR1PTGDR2NPC1MEN1KMT2A | |
| SCHEMBL852910 | 0.75 | PTGDR2 (0.46) | FFAR1PTGDR2POLBKMT2ACYP3A4 | |
| SCHEMBL28465228 | 0.72 | LMNA (0.39) | PTGDR2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18104854 | 0.72 | FFAR1 (0.43) | FFAR1PTGDR2LMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096770-A | ADMINISTERING ORALLY OR PARENTALLY, TO A PATIENT AN ANTHRANILIC ACID DERIVATIVE FOR REDUCING THE ADVERSE EFFECTS OF SMOOTH MUSCLE CONTRACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1003713-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007670-A1 | ANTHRANILIC ACID ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |