Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386053 | 0.83 | FFAR4 (0.52) | FFAR4PPARGPPARASLC13A5AR | |
| SCHEMBL27014290 | 0.78 | SRD5A2 (0.40) | FFAR4S1PR1FFAR1 | |
| SCHEMBL8058320 | 0.77 | FFAR1 (0.45) | SMN1; SMN2LMNAMAPTTDP1FFAR1 | |
| SCHEMBL854121 | 0.76 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27014285 | 0.76 | EPHX2 (0.41) | FFAR4PPARGPPARASMN1; SMN2LMNA | |
| SCHEMBL124863 | 0.74 | NPSR1 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25382322 | 0.74 | SLC6A7 (0.42) | FFAR4PPARGPPARASLC13A5AR | |
| SCHEMBL3966267 | 0.73 | AR (0.50) | FFAR4PPARGPPARASLC13A5AR | |
| SCHEMBL25382661 | 0.72 | NOTUM (0.44) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25382828 | 0.72 | AKR1C3 (0.48) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912679-B2 | Aryl alkynamide derivatives | ASTELLAS PHARMA, INC. (JP) | 2024-02-27 | — | — | US | disclosed |
| US-11912679-B2 | Aryl alkynamide derivatives | ASTELLAS PHARMA, INC. (JP) | 2024-02-27 | — | — | US | disclosed |
| US-20240018113-A1 | ARYL ALKYNAMIDE DERIVATIVES | ASTELLAS PHARMA, INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| US-20240018113-A1 | ARYL ALKYNAMIDE DERIVATIVES | ASTELLAS PHARMA, INC. (JP) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018113-A1 | ARYL ALKYNAMIDE DERIVATIVES | STING1, IRF3, TBK1 | FFAR4 2933/4885PPARG 4665/4885PPARA 4258/4885 |
| US-11912679-B2 | Aryl alkynamide derivatives | STING1, IRF3, TBK1 | FFAR4 2933/4885PPARG 4665/4885PPARA 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.