SCHEMBL8058358

SCHEMBL8058358

CC(C)[O-].CC(C)[O-].CCCC(=O)NC1CCCC(C(C)C)(C(C)C)C1.CCCC(=O)N[Ti+2]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
CNR2 P34972 2/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.31
EPHX2 P34913 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8071519 0.95 SMN1; SMN2 (0.38) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8069038 0.91 SMN1; SMN2 (0.35) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8057784 0.88 MTNR1A (0.31) SMN1; SMN2MTNR1AMTNR1BHPGD
SCHEMBL8067398 0.87 SMN1; SMN2 (0.37) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
Hydrochloric Acid SCHEMBL8073534 0.86 SMN1; SMN2 (0.36) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8068965 0.86 SMN1; SMN2 (0.36) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8068453 0.85 SMN1; SMN2 (0.36) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8071405 0.84 SMN1; SMN2 (0.35) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8057813 0.83 CNR2 (0.35) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
Hydrochloric Acid SCHEMBL8072210 0.83 MTNR1A (0.32) SMN1; SMN2MTNR1AMTNR1BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127496-A POLYMERIZING OLEFINICALLY UNSATURATED COMPOUNDS IN PRESENCE OF METALLOCENE CATALYST SYSTEM CONTAINING A COMPOUND CAPABLE OF FORMING METALLOCENIUM IONS BASF AKTIENGESELLSCHAFT (DE) 2000-10-03 US disclosed
US-6077965-A Metal complexes with an adamantane-like structure BASF AKTIENGESELLSCHAFT (DE) 2000-06-20 US disclosed