Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8073534

CCCC(=O)NC1CCCC(C(C)CC)(C(C)CC)C1.CCCC(=O)N[Ti+2].[Cl-].[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
CNR2 P34972 2/20 0.33
EPHX1 P07099 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.31
EPHX2 P34913 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8069038 0.95 SMN1; SMN2 (0.35) SMN1; SMN2MTNR1AMTNR1BCNR2EPHX1
Hydrochloric Acid SCHEMBL8071519 0.90 SMN1; SMN2 (0.38) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
Hydrochloric Acid SCHEMBL8066852 0.88 EPHX1 (0.33) SMN1; SMN2MTNR1AMTNR1BEPHX1HPGD
SCHEMBL8058358 0.86 SMN1; SMN2 (0.36) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8068959 0.83 EPHX1 (0.32) EPHX1
Hydrochloric Acid SCHEMBL8073383 0.83 EPHX1 (0.35) EPHX1ALDH1A1EPHX2L3MBTL1TSHR
Hydrochloric Acid SCHEMBL8071885 0.81 SMN1; SMN2 (0.38) SMN1; SMN2MTNR1AMTNR1BALDH1A1GAA
Hydrochloric Acid SCHEMBL8068497 0.80 SMN1; SMN2 (0.37) SMN1; SMN2MTNR1AMTNR1BALDH1A1GAA
SCHEMBL8067398 0.80 SMN1; SMN2 (0.37) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1
SCHEMBL8071405 0.79 SMN1; SMN2 (0.35) SMN1; SMN2MTNR1AMTNR1BCNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127496-A POLYMERIZING OLEFINICALLY UNSATURATED COMPOUNDS IN PRESENCE OF METALLOCENE CATALYST SYSTEM CONTAINING A COMPOUND CAPABLE OF FORMING METALLOCENIUM IONS BASF AKTIENGESELLSCHAFT (DE) 2000-10-03 US disclosed
US-6077965-A Metal complexes with an adamantane-like structure BASF AKTIENGESELLSCHAFT (DE) 2000-06-20 US disclosed