Phosphoric Acid

Phosphoric Acid

SCHEMBL8058372

O=C(O)O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.58

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.56
CA1 P00915 1/20 0.56
CA9 Q16790 1/20 0.56
LMNA P02545 3/20 0.44
BLM P54132 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
KMT2A Q03164 1/20 0.44
SLC34A1 Q06495 1/20 0.39
MMP2 P08253 2/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FDPS P14324 1/20 0.36
PEPD P12955 1/20 0.35
CA4 P22748 2/20 0.33
MMP3 P08254 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9678210 1.00 CA2 (0.56) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL3880757 1.00 CA2 (0.56) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL23721810 1.00 CA2 (0.56) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL981031 1.00
Phosphoric Acid SCHEMBL2771650 0.95 CA2 (0.50) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL6247170 0.95 CA2 (0.50) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL10515585 0.95 CA2 (0.50) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL21184393 0.95 CA2 (0.50) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL21184392 0.95 CA2 (0.50) CA2CA1CA9LMNABLM
Phosphoric Acid SCHEMBL23539926 0.95 CA2 (0.50) CA2CA1CA9LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779884-B1 IMIDIC ACID DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 2000-05-03 EP disclosed
US-4317715-A Process for the selective froth-flotation of phosphate and carbonate minerals from finely-divided phosphate-carbonate-silicate ores or concentrates OUTOKUMPU OY (FI) 1982-03-02 US disclosed
US-3934049-A ALKALI METAL PYROPHOSHATE AND CARBONATE, ALKALINE EARTH METAL ORTHO-PHOSPHATE, AND PREGELATINIZED STARCH OR GUMS STAUFFER CHEMICAL COMPANY (US) 1976-01-20 US disclosed