Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | USP1 | O94782 | 3/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454616 | 0.84 | HTR2C (0.41) | SLC13A5CNR2 | |
| SCHEMBL7439313 | 0.81 | MAOB (0.46) | SLC13A5 | |
| SCHEMBL8540798 | 0.73 | HTR2C (0.44) | SLC13A5CNR2 | |
| SCHEMBL8542783 | 0.72 | MAOB (0.42) | SLC13A5 | |
| SCHEMBL5115977 | 0.72 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL6885675 | 0.72 | MAOB (0.41) | SLC13A5 | |
| SCHEMBL7453648 | 0.71 | HTR2C (0.40) | — | |
| SCHEMBL7100010 | 0.70 | HTR2C (0.43) | — | |
| Hydrochloric Acid SCHEMBL1742023 | 0.69 | HTR2C (0.44) | — | |
| SCHEMBL5497223 | 0.69 | GRIN1 (0.36) | TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017385-A1 | USE OF 4-SUBSTITUTED TETRAHYDROPYRIDINES FOR MAKING MEDICINES ACTING ON TGF-beta 1 | SANOFI-SYNTHELABO (FR) | 2000-07-12 | — | — | EP | claimed |
| WO-1998053821-A1 | USE OF 4-SUBSTITUTED TETRAHYDROPYRIDINES FOR MAKING MEDICINES ACTING ON TGF-β1 | SANOFI-SYNTHELABO (FR) | 1998-12-03 | — | — | WO | claimed |